Vancouver Feline Hospital - Cat Veterinary Clinic

Rx

n

Comment

Products

Lufeneron alone^3,4

Fails to prevent infection^5,6

Program

Topical antifungal cream

For small localized lesions; prevent ingestion

Conofite

Clorhexidine

For small localized lesions; also as part of shampoo; antifungal residual effect cumulative

Hibitane

Iodine

Potassium or sodium iodide as a tincture dabbed to the spot; oral or iv (KI 1g/35g max 2g po in pigs; NaI 10% soln 1g/14kg iv in cattle) NOT recommended!!! Vioform both antifungal&antibacterial, don't get in eyes; not generally recommended these days.⁷

Lugol's

Betadine

Vioform (iodochlorhydroxyquin 3%)

Antifungal shampoo

Whole cat wet to the bone twice weekly (once weekly has also worked) for at least 8 treatments; suggest do in clinic; let sit wet and sudsy 5-10 mins; dry cat poperly to prevent matting or lion-shave long-haired cat; often combined with systemic antifungals

Nizoral (ketoconazole)

Imaverol (enilconazole)

Malaseb (miconazole plus chlorhexidine)

Systemic antifungals

Do not use in cats with liver disease; may see raise in liver enzymes during treatment – suggest get baseline values before starting treatment and monitor values 10d after starting treatment; the newer drugs have less side-effects but are more expensive

Griseofulvin

Sporanox (itraconazole)

With a fatty meal (normal cat food)

Copper & Zinc sulphate

Farm remedy, 0.1-2% aq.solns, astringent, caustic-.would not recommend for a cat.⁷

Organic acids

Keratolytic activity - fungistatic, salicylic acid needs presence of water for effect, repeated applications cause irritation - would not recommend for a cat.⁷

Caprylic acid

Propionic acid

Undecylenic acid

Benzoic acid

Salicylic acid

Combinations.

Sulphur

Miticidal ear prep⁷

Lime sulfur dips?

Monosulfiram (tetmosol)

Captan

Carcinogenic, 1tbs/l water daily

would not recommend for a cat ⁷

Tolnaftate

1%, can be administered with griseofulvin would not recommend for a cat ⁷

Dichlorophen

Taenicide, also effective topical fungicide, 2% ointments, tinctures; apply q 2-3days; bactericidal against staph.aureus.

would not recommend for a cat ⁷

Rx

n

Comment

lufeneron alone^3,4

Treatment failures at 50mg/kg, suggested min dose 100mg/kg repeated after 14d

Fails to prevent infection^5,6

lufeneron (60mg/kg po day 0 and day 30) plus enilconazole (0.2%) rinses weekly¹

100

Fungal cultures

Mean number of fungal colonies decreased rapidly during first 15d rx, remained stable next 45d, then increased from d60 to d90 (end of study) Environment was treated with enilconazole weekly for first 30d. Lufeneron protocol worked better in the cattery with lower population density that managed to significantly decrease environmental contamination. Cure took weeks, some remained culture positive, no definite eradication achieved

griseofulvin (micronised 25mg/kg po bid 5 weeks) plus enilconazole (0.2%) rinses weekly¹

Do not use in pregnant cats - griseofulvin is teratogenic,

also toxic to Persians, Himalayans, Siamese, Abyssinians and FIV+ cats²

Terbinafine

No controlled studies done in catteries on these drugs

Ketoconazole

Itraconazole